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What is Polycystic Kidney Disease? Polycystic kidney disease is a genetic disorder that causes the kidneys to become enlarged and filled with fluid-filled cysts. The condition can be inherited or acquired, but most cases are due to an autosomal dominant gene mutation in one of two genes: PKD1 or PKD2. Polycystin 1 mutations cause polycystic kidney disease type I; polycystins 2 and 3 mutations lead to polycystic kidney disease types II and III respectively. In addition to causing renal failure, patients may develop liver problems, heart defects, diabetes mellitus, hypertension, intracranial hemorrhage, and other complications. Symptoms of Polycystic kidney disease Polycystic kidney disease symptoms can include: high blood pressure, back or side pain, blood in your urine, increased size of your abdomen due to swelling of the kidneys, headaches, kidney stones, urinary tract infection, and/or kidney failure. Symptoms usually appear gradually over time. Some people have no signs or symptoms at all until they reach end-stage renal disease. You will need to see your doctor if you experience any of these symptoms: Abdominal distention Pain in your lower back or sides FeverNausea Vomiting Weight loss Fatigue Difficulty sleeping Unexplained bruising Darker colored stools than usual Homoeopathic Medicines : Kali Chloricum 30 : Kali chloricum is best for polycystic kidney disease with violent nephritis. The urine is scanty, dark, albuminous, and contains casts. Lycopodium Clavatum 30 : Lycopodium is an effective remedy for polycystic kidney disease with kidney failure. There is a high level of creatinine in the blood. Urine scanty cries before urinating, red sand in urine, must strain, suppressed or retained. Urine milky and turbid. Sometimes haematuria. Urine is burning and hot. The right kidney is mainly affected. Mercurius Corrosivus 30 : Mercurius cor is indicated in a large white kidney. The urine is scanty, red, with albumin and casts. The urine is hot, burning, and passed drop by drop with much tenesmus of the bladder. There is lumbar pain and great dyspnea. Also, there is swelling of the feet. Plumbum Metallicum : Plumbum met is prescribed where there are granular degenerations of the kidneys with a tendency to uraemic convulsions. Kidney contracted. There is dropsy, sallow face, emaciation, and Oedema about the ankles. The urine is albuminous having low specific gravity. The patient is always constipated. Phosphorus : Polycystic kidney disease with nephritis. There is hematuria in acute nephritis, urinates pure blood. Urine turbid, brown with red sediment. There is lassitude of the whole body, hands, and feet icy cold, sleepiness there is edema of the upper eyelids and face. Vomiting and gastric symptoms are usually present. Note – Above medicines are for knowledge purpose only. Take the medication only after doctor’s consultation. Do not self medicate